ea0092ps1-05-05 | Thyroid hormone diagnostics 1 | ETA2023
George Augustine
, Bossowski Artur
, Frommer Lara
, Hatun Burak
, Konig Jochem
, Lupo Mark
, Wolf Jan
, Kahaly George
Background: Thyrotropin receptor (TSH-R) blocking autoantibodies (TBAb) are present in 10-15% of patients with autoimmune thyroid disease (AITD). TBAb are functional and clinically relevant. This multicenter study compares the sensitivity and specificity of five immunoassays for the measurement of TBAb and introduces a novel and ultra-rapid TBAb bioassay.Methods: Serum samples from AITD patients were tested with two TSH-R binding immunoassays (Cobas e411...